PALMOPLANTAR PUSTULAR PSORIASIS INDUCED BY ADALIMUMAB A CASE REPORT AND LITERATURE REVIEW

PALMOPLANTAR PUSTULAR PSORIASIS INDUCED BY ADALIMUMAB A CASE REPORT AND LITERATURE REVIEW

One example is interferon-alpha, which plays an important role in the initiation of psoriasis. A skin biopsy specimen showed psoriasiform epidermal hyperplasia associated with parakeratosis, telangiectatic blood vessels, perivascular lymphocytic infiltrate, and occasional neutrophils in the papillary dermis and lower epidermis. Beta-blockers, also known as beta-adrenergic receptor antagonists, have been among the drugs most strongly linked to plaque psoriasis exacerbation. Study concept and design: Inverse psoriasis induced by terbinafine.

The full terms of this license are available at https: There were a few telangiectatic blood vessels in the papillary dermis associated with perivascular lymphocytic infiltrate and occasional neutrophils. However, in some cases, so-called psoriasiform skin lesions are described. One example is interferon-alpha, which plays an important role in the initiation of psoriasis. Severe pustular psoriasis provoked by oral terbinafine.

Palmoplantar pustular psoriasis induced by adalimumab: a case report and literature review.

Finally, interferon-gamma, which was studied as a potential psoriasis treatment in the early s, has been described to induce psoriasis at the injection site of interferon-gamma. Dr Shojania has received research funding and speaking honoraria from Abbott, Amgen, Schering, and Centocor.

Back to top Article Information.

palmoplantar pustular psoriasis induced by adalimumab a case report and literature review

Recognizing potential drug-related psoriasis is of clinical relevance to allow an optimal management of psoriasis. Suspected medications may be discontinued and switched to an alternative medication when possible, while the psoriasis should be treated according to standard guidelines.

Traditionally, drugs that are strongly implicated in psoriasis include beta-blockers, lithium, synthetic antimalarial drugs, and imiquimod.

Register for email alerts with links to free full-text articles Access PDFs of free articles Manage your interests Save searches and receive search alerts. The list of drugs that have associations with drug-related psoriasis is quite extensive.

  DEDIKASYON SA TERM PAPER

Palmoplantar pustular psoriasis induced by adalimumab: a case report and literature review.

peoriasis A year-old woman with rheumatoid arthritis and no personal or family history of psoriasis was treated with rofecoxib, leflunomide, and etanercept. Geller L, Kellen R. Imiquimod is a topical toll-like receptor TLR 7 agonist that can activate cutaneous plasmacytoid dendritic cells to produce interferons.

Of note, the available evidence supporting the associations of drug-related psoriasis with various drugs is limited predominantly to anecdotal single-case reports or retrospective case series.

There is a single case of the development of psoriasiform diaper rash linked to treatment with oral propranolol in an month-old girl.

[Full text] Drug-induced psoriasis: clinical perspectives | PTT

By accessing the work you hereby accept the Terms. Anti-tumor necrosis factor-induced palmoplantar psoriasis: Most patients with anti-TNF-alpha-induced psoriasis can be managed with topical corticosteroids, but switching to a different TNF-alpha blocker or to a biologic with a different treatment target may prove helpful.

Sign in to access your subscriptions Sign in to your incuced account. Create a free personal account to download free article PDFs, sign up for alerts, customize your interests, and more. Assessment of the Naranjo inducced drug reaction probability scale could be used as a practical tool to better differentiate drug-related psoriasis.

Drug-induced psoriasis: clinical perspectives

Four patients treated their skin disease successfully with topical corticosteroids, while 9 patients continued to have persistent skin disease despite topical therapy. Such mechanistic insights have helped to eludicate the pathophysiological pathways underlying psoriasis. You can learn about what data of yours we retain, how it is processed, who it is shared with and your right to have your data deleted by reading our Privacy Policy.

  CRM IMPLEMENTATION CASE STUDY .PPT

Exposure to certain drugs can elicit an induction or exacerbation of psoriasis. Table 2 The Naranjo adverse drug reaction probability scale Note: Taken together, recognizing potential drug involvement in psoriasis is of clinical relevance to allow an optimal management of psoriasis. Summative statistics for our case series are listed in Table 2.

palmoplantar pustular psoriasis induced by adalimumab a case report and literature review

Upon discontinuation of the implicated drug, the psoriasis exacerbation can decrease ie, drug-induced psoriasis. In most cases, the histopathology of a drug-induced psoriasis is virtually indistinguishable from that of conventional psoriasis.

palmoplantar pustular psoriasis induced by adalimumab a case report and literature review

Drafting of the manuscript: Ritchlin, MD; Bruce E. A tool to help to better discern potential causal drug relations is the Naranjo adverse drug reaction probability scale.

The human-specific primary antibody used was anti—myxovirus-resistance protein A MxA monoclonal antibody clone M Pustular psoriasis induced by hydroxychloroquine: Examples of these include beta-blockers, lithium, antimalarial drugs such as chloroquine, interferons, imiquimod, and terbinafine.

Search in Google Scholar for Altalhab S. Timolol drops causing reversible psoriatic fingernail changes. Successful treatment of recalcitrant palmoplantar pustular psoriasis with sequential use of infliximab and adalimumab.